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陈清奇

陈清奇,男,祖籍湖南省安仁县,中国旅美化学家和药学家, 1993年毕业于北京大学获理学博士学位,研究 领域和研究方向为新药研发与药物合成化学。

从1993 年~1998年,曾先后在奥地利(Johannes-Kepler University Linz),美国(University of Nevada Reno), 加拿大(The University of British Columbia) 等大学留学和工作,主要从事新药研发、天然产物全合成、药物化学等方面的研究。1998 年起进入生物制药和生物技术工业界发展,曾先后在美国数家生物医药高科技公司从事抗癌新药研究和开发,曾担任各种关键职位, 历任高级科学家, 研究课题负责人, 研究室主任和副总裁和总裁,在新药研发, 药物筛选, 药品配方, 药物化学合成和生产工艺,新药临床前研究等方面有比较丰富的经验。 此外陈清奇曾在2002年 ~ 2005年与朋友起在美国加州旧金山市创办一家生物医药公司,成功地向美国市场推出了2种具有疗效功能的保健产品。

陈清奇博士于2008年在美国北卡罗莱纳州的研究三角区创办了MedKoo医药科技公司。该公司目前正在建设一个全球最大的抗癌化合物库。公司的主要业务是向全球所有从事抗癌药物研究开发的制药企业,科研机构和大专院校提供最好的抗癌药物、抗癌化学试剂、抗癌药原料和化学中间体。 MedKoo 的目标是打造全球规模最大、品种最多、类别最全和质量最好的小分子抗癌化合物库。MedKoo的抗癌药库将由下列5个分子库组成:(1)上市抗癌药库:该库将含有大约100个全球已批准上市的小分子抗癌化合物;(2)抗癌候选药物库:该分子库含有大约400个世界各国正在临床研究中抗癌小分子候选药物;(3)同系抗癌分子库:该分子库将含有多个化学结构类似或抗癌机制类似的分子包;(4)抗癌分子预制模块库:该库主要含有用于组建抗癌目标分子的分子模块包; (5)同位素标记抗癌分子库.

1. 在新药研发方面: 在陈清奇参与或负责部分研发工作的药物中,已有3种获美国FDA及全球八十多个国家批准上市,另外还有数种进入了临床试验,10余种进入临床前试验阶段;

2. 曾参与开发了3个药物的化学全合成生产工艺,这些成果已应用于实际生产中. 这些药物目前正在全球八十多个国家销售;

3. 迄今为止编写和出版了总字数超过600万的6部药学和化学著作:

-- 《小分子药物的生产制造与化学全合成路线手册》,湖南科技出版社(2008年4月);

-- 《美国药品专利研究指南》,科学出版社(2008年6月由);

-- 《 新药化学全合成手册1999~2007》,科学出版社(2008年7月);

-- 《美国抗癌药物化学合成速查》,科学出版社(2009年1月);

-- 《抗癌新药研究指南》,科学出版社(2009年2月);

-- 《抗癌药物分子库》,科学出版社(2010年2月)。

4. 在国际知名专业学术刊物上已发表了90多篇科技论文, 10多项发明专利。

5. 曾于1999年入选中国科学院”百人计划”教授及博导, 目前兼任华南师范大学化学系药物化学和新药研发客座教授。

1998-2000:The University of British Columbia (博士后研究员,导师:Dr.David Dolphin).

1995-1998:The University of Nevada Reno (博士后研究员,导师:Dr.David Lightner).

1995-1995:Technical University of Vienna(访问教授,导师:Dr.Ulrich Jordis).

1993-1995:Johannes-KeplerUniversity Linz (博士后研究员,导师:Dr.Helinz,Falk).

1990-1993:北京大学化学系(博士生,指导老师:金声教授,马金石教授)。

1985-1987:延边大学化学系(有机化学研究生班学生)。

1979-1982:郴州师范专科学校化学科(该校现改名为:湘南学院)。

2009 - 现在: MedKoo Biosciences (美国)。

2006 - 2009:Erimos Pharmaceutical Inc(美国)。.

2004-2006:MedTox Diagnostics Inc(美国)。

2002-2004:BioMarin Pharmaceuticals Inc(美国)。

2000-2002:Synapse Technologies Inc(加拿大)。该公司于2002年被BioMarin公司收购。

1999-2000:University of British Columbia (加拿大) and QLT Inc(加拿大)。

1987-1990:北京市食品工业研究所。

1983-1985:湖南安仁县平背中学任老师。

1982-1983:湖南安仁县第四中学任老师。

赵云清:著名的成功学大师,现山东云清新技术开发有限公司老总

汪秋安:理学博士,2000年至2001年在比利时王国根特大学完成博士后研究回国。现为湖南大学化学化工学院副教授、化学系主任。

杨定乔广东省化学化工学会常务理事。广东省高等院校化学化工协会常务理事。华南师范大学 化学与环境学院 有机化学研究所所长 教授

陈清奇的发明专利(到2008年为止)

6 Qingqi Chen, Jessica Blomberg. 题目待公开, (PCT and US provisional patent application, filed in August, 2008)

5. Qingqi Chen, Bing Li, Rong Li, Manufacturing of fabric sheet contained grass seeds, super-aborsbent, control released fertilizer, and protective agents, Chinese Patent, CN1994038 (2006).

4. Chen, Qingqi; Lopez, Rocio A.; Heller, Jonathan D.; Morris, Amanda Jean. Preparation of nordialkoxyguaiaretic acid derivatives for use as therapeutic agents. PCT Int. Appl. WO 2008042896 (2008).

3. Chen, Qingqi; Lopez, Rocio A.; Heller, Jonathan D.; Morris, Amanda Jean. Tetra-o-substituted butane-bridge modified nordihydroguairetic derivatives, their synthesis and pharmaceutical use. PCT Int. Appl. WO 2008042921 (2008).

2. Qingqi Chen, Damian Sowa, Reinhard Gabathuler, The Use Of Isocyanate Linkers for the Synthesis Of Hydrolyzable Active Agent Biopolymer Conjugates PCT Patent, WO-2004008101 (2004); US Patent application: 20060029586 (Feb 9, 2006); 20040176270 (Sept 9, 2004).

1. Reinhard Gabathuler, Gerrassimos Kolaitis, Robert Charles Brooks, Qingqi Chen, Delara M. Karkan, Gavin D. Arthur, Jean Paul St. Pierre, Wilfred Jeffries, Chemotherapeutic Agents conjugated to P97 and Their Methods of Use in Treating Neurological tumors, PCT Patent, WO-0213843 (2002), US Patent application: 20020119095 (Aug. 22, 2002).

陈清奇已发表的科学研究论文(按最新发表排序:

2008

89 Karkan D, Pfeifer C, Vitalis TZ, Arthur G, Ujiie M, Chen Q, Tsai S, Koliatis G, Gabathuler R, Jefferies WA. A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier. PLoS ONE. 2008 Jun 25;3(6):e2469.

2007

88 Zhang G, Yang G, Wang S, Chen Q, Ma JS, A highly fluorescent anthracene-containing hybrid material exhibiting tunable blue-green emission based on the formation of an unusual "T-shaped" excimer. Chemistry. 2007;13(13):3630-5.

87 Guoqi Zhang, Guoqiang Yang*, Shuangqing Wang, Qingqi Chen, Jin Shi Ma*, A Highly Fluorescent Anthracene-Containing Hybrid Material Exhibiting Tunable Blue-Green Emission Based on the Formation of an Unusual "T-Shaped" Excimer, Chemistry - A European Journal, 2007, 13(13), 3630

86 Zhong Li, Dingqiao Yang, Reinhard Gabathuler, Qingqi Chen,* Synthesis of novel heterobifunctional isocyanato cross-linkers and their applications for the preparation of 10-hydroxycamptothecin and SN-38 conjugates with melanotransferrin p97, Synthetic Communications, 2007, 37, 1899 1915.

2006

85 Guo-Qi Zhang, Guo-Qiang Yang*, Lin-Na Zhu, Qing-Qi Chen, Jin-Shi Ma*, A potential fluorescent sensor for Zn2+ based on a selective bis-9-anthryldiamine ligand operating in buffer, Sensors and Actuat. B-Chem. 2006, 114, 995-1000.

2005

84 Guo-qi Zhang, Guo-qiang Yang*, Lan-ying Yang, Qing-qi Chen, Jin-Shi Ma*, Synthesis, Characterization and Photophysical Properties of Novel Dinuclear Silver(I) and Mononuclear Palladium(II) Complexes with 1,2-Bis[(anthracen- 9-ylmethyl)amino]ethane, Eur. J. Inorg. Chem. 2005, 19191926

83 Guoxi Zhang; Guoqiang Yang; Qingqi Chen; Jinshi Ma*; Novel Network Polymers Formed by Self-Assembly of Silver Nitrate and Pyrrol-2-yl-methyleneamine Ligands with Flexible Spacers Cryst. Growth Des. 2005; 5(2); 661-666

2004

82. .Lanying Yang, Xufeng Shan, Qingqi Chen, Jin Shi Ma*, Self-assembly of 1,4-bis(pyrrol-2-ylmethyleneamine)butane mediated by Ni(II) and weak intermolecular interactions, J. Chem. Res. 2004, 636-637

81. Xufeng Shan, Lanying Yang, Wei Li, Qingqi Chen, Zhengping Wang, Jiming Hu, Jinshi Ma, Synthesis, Fourier-transform Raman and Infrared Spectroscopic Analysis, and Crystal Structure of (NiL)2, (L = Bis(2,4-dimethyldipyrrin-3-yl)methane, J. Chem. Crystal. 2004, 34(7), 433 439.

80. Qingqi Chen*, Reinhard Gabathuler, Synthesis of Camptothecin Melantotransferrin (P97) Conjugate Through A Carbamate Bond, Synth. Commun. 2004, 34(13), 2415 - 2424.

79. Qingqi Chen*, Reinhard Gabathuler, Efficient Synthesis of Polyethylene Glycol Mono-Carboxylate Via Michael Conjugate Addition, Synth. Commun. 2004, 3 (13), 2425 - 2432.

78. Qingqi Chen*, Reinhard Gabathuler, Efficient Synthesis Of Doxorubicin Melanotransferrin P97 Conjugates Through SMCC Linker, Synth. Commun. 2004, 34(13), 2407 - 2414.

77. Zhikun Wu, Qingqi Chen, Guoqiang Yang, Chengbin Xiao, Jingang Liu, Shiyong Yang, Jin Shi Ma, Novel fluorescent sensor for Zn(II) based on bis(pyrrol-2-yl-methyleneamine) ligands, Sensors and Actuat. B-Chem. 2004, 99,511515.

76. Lanying Yang, Yi Zhang, Guoqiang Yang, Qingqi Chen, Jin Shi Ma*. Zn(II) and Co(II) Mediated self-assembly of bis(dipyrrin) ligands with a methylene spacer bridged at 3,3’-poistions and their optical properties. Dyes and Pigments. 2004, 62(1), 27-33.

75 Lanying Yang, Xufeng Shan, Qingqi Chen, Zhengping Wang, Jin Shi Ma*. The first silver(I) side-on η2 coordination network formed by self-assembly of bis(pyrrol-2-yl-methyleneamine). Eur. J. Inorg. Chem. 2004, 1474- 1477

74. Lanying Yang, Qingqi Chen, Yan Li, Shaoxiang Xiong, Genpei Li, Jin Shi Ma*. Self-assembly of bis(pyrrol-2-yl-methyleneamine) ligands with CuII controlled by bridging spacers (-(CH2)n-) and weak intermolecular hydrogen bonding CH…Cu. Eur. J. Inorg. Chem. 2004, 1478-1487.

73. Zhikun Wu, Guoqiang Yang, Qingqi Chen, Jingang Liu, Shiyong Yang, Jinshi Ma, One-pot synthesis and self-assembly of double stranded helical metal complexes, Inorg. Chem. Comm. 2004, 7, 249-252.

72. Lanying Yang, Yi Zhang, Qingqi Chen, Jin Shi Ma*. Molecular Rectangle Formed by Head-to-tail Self-Assembly of 1-(Dipyrrin-2-yl)-1’-(dipyrrin-3-yl)methane. Monatsh. Chem. 2004, 135, 223-229

2003

71. Lanying Yang, Qingqi Chen, Guoqiang Yang, Jinshi Ma. Self-assembly of bis(pyrrol-2-yl-methyleneamine)s bridged by flexible linear carbon chains. Tetrahedron, 2003, 59(50), 100037-100041.

70. Zhikun Wu, Qingqi Chen, Shaoxiang Xiong, Bin Xin, Zhenwen Zhao, Lijin Jiang, JinShi Ma, Novel Double Stranded Hexlicates, Triangle and Square Formed By Self Assembly of Pyrrol-2-yl-methyleneamines with Zinc (II), Angew. Chem. Int. Ed, 2003, 42(28), 3271-3274.

69 Qingqi Chen, David Dolphin, “3,3’-Dipyrrolylsulfides, Useful Building Blocks for the Syntheses of Macrocycles Containing Dipyrromethene Units”, Can. J. Chem. 2003, 81(9), 988-991.

68 Qingqi Chen, Damian A. Sowa, Jianlin Cai, Reinhard Gabathuler, Efficient One-Pot Synthesis Of Doxorubicin Conjugates Through Its Amino Group To Melanotransferrin P97, Synth. Commun. 2003, 33(14), 2399-2419.

67 Qingqi Chen, Damian A. Sowa, Jainlin Cai, Reinhard Gabathuler, Synthesis Of Doxorubicin Conjugates Through Hydrazone Bonds To Melanotransferrin P97, Synth. Commun. 2003, 33(14), 2375-2388.

66 Qingqi Chen*, Damian A. Sowa, Reinhard Gabathuler, Synthesis Of Doxorubicin Conjugates Through 14-Hydroxy Group To Melanotransferrin P97, Synth. Commun. 2003, 33(14), 2389-2398.

65 Qiuan Wang, Yanlin Li, Qingqi Chen, A Conventient, Large Scale Synthesis of Trans-(+)-Sobrerol, Synth. Commun. 2003, 33(12), 2125 2134.

64 Qingqi Chen, David Dolphin, Cyclooctapyrroles, Novel Macrocycles Containing Biladiene-a,c Units”, Tetrahedron, 2003, 59(6), 871-875.

2002

63 Qingqi Chen, David Dolphin, Fast, Efficient Synthesis of Linear Polydipyrromethene, Can. J. Chem, 2002, 80(12), 1668-1675

62 Qingqi Chen, Yongjun Zhang, David Dolphin*, Synthesis and Self-assembly of Novel Tetra- and Hexapyrroles Containing Dipyrrins Linked by A Sulfur Bridge at the -Position, Tetrahedron Lett. 2002, 43(46), 8413-8416.

61. Yi Zhang, Qingqi Chen, Zheming Wang, Chuhua Yan, Genpei Li, Jinshi Ma*, Tetra-N-Confused Cyclohexapyrrole: The Unusual Product Formed by Condensation of 3,3’-Dipyrromethane with Tripyrrin-aldehyde, J. Org. Chem. 2002, 67(14), 4997-5000.

60. Peng Wang, Qingqi Chen, Yi Zhang, Jin-shi Ma, An Efficient One-Step Conversion of Biliverdins to 14-formyl-Tripyrrinones, Org. Prec. Prep. Int. 2002, 34(2), 182-187.

59 Qingqi Chen*, Tianyu Wang, Yi Zhang, Qiuan Wang, Jinshi Ma, A Facile, Highly Efficient Synthesis of Fully N-confused Calix[5]pyrroles, Synth. Comm. 2002, 32(7), 1041-1049.

58 Qingqi Chen*, Tianyu Wang, Yi Zhang, Qiuan Wang, Jinshi Ma, Doubly N-confused Calix[4]pyrrole Prepared by Rational Synthesis, Synth. Comm. 2002, 32 (7), 1051-1058.

57 Qingqi Chen*, Tianyu Wang, Yi Zhang, Qiuan Wang, Jinshi Ma, Large Scale, Efficient Synthesis of 9-Unsubstituted dipyrrinone, Synth. Comm. 2002, 32(7), 1031-1040.

2001

56 Jiming Hu, Tianyu Wang, Damien Moigno, Minawer Wumaier, Wolfgang Kiefer, Jungang Mao, Qiaofeng Wu, Fei Niu, Yinghong Gu, Qingqi Chen, Jinshi Ma, Haitao Feng, Fournier-transform Raman and infrared spectroscopic analysis of dipyrrinones and mesobilirubins, Spectrochimica Acta Part A, 2001, 57, 27372743

55 Bin Tu, Qingqi Chen, Fang Yan, Jinshi Ma*, Karl, Grubmayr, Heinz Falk, Efficient Routes to -Chloroalkyl Bilirubins and C12-N22 Bridged Biliverdins, Monatshefte fur Chemie 2001, 132, 693-705.

54 Hao Cheng, Dehe Zhang and Jinshi Ma*, Qingqi Chen, Synthesis of 5-p-[N-(2-Prrolidinonephenyl-10,15,20-Triphenylporphyrin), Synth. Comm. 2001, 31, 1941-1945.

53 Qingqi Chen*, David Dolphin, A Highly Efficient Preparation of N-Confused Cyclodecapyrroles Tetrahedron Lett. 2001, 42, 3263-3265.

52 Qingqi Chen, David Dolphin*, A highly Efficient Preparation of 3,3'-dipyrrolylsuflide, Synthesis, 2001, 40-42.

2000

51 Qiuan Wang*; Zhaoxu Sun; Qingqi Chen, A Facile Total Synthesis of 1,4-Benzodioxane Type Neolignans Eusiderin G, Chinese J. Org. Chem.( = Youji Huaxue), 2000, 20(6), 910-914.

50 Jiming Hu*, Damien Moigno, Wolfgang Kiefer, Jinshi Ma, Qingqi Chen, Changqi Wang , Haitao Feng, Jingkai Shen, Fei Niu, Yinghong Gu, Fourier-transform Raman and infrared spectroscopic analysis of novel biliverdin compounds, Spectrochimica Acta Part A 2000, 56, 23652372.

49 Micheal T. Huggins, Adrianne K. Tipton, Qingqi Chen, David A. Lightner*, Hydrogen-Bonded Double Strands. Crystal Structure and Spectroscopic Properities of a 2,2-Dipyrryl Ketone, Monatshefte fur Chemie 2000, 131, 825-838.

48 Qingqi Chen*, Xiaoli Li, and Bingzi Chen, An Efficient Preparation of 1,2-Bisdipyrrin-9-ylene)-ethane, the First Fully Conjugated b-Homobilin. Synthetic Communications 2000, 30(3), 383-396.

1999

47 Qingqi Chen, Micheal T. Huggins, David Lightner*; Wilma Norona, and Antony F. McDonagh, Synthesis of the First 10-Oxo-Bilirubin. Effects of the Oxo Group on Conformation, Transhepatic Transport and Glucuronidation, J. Am. Chem. Soc. 1999, 121, 9253-9263.

1998

46 Qingqi Chen, David. A. Lightner*; Hemirubin: An Intramolecularly Hydrogen Bonded Analog for One-Half Bilirubin, J. Org. Chem. 1998; 63(8); 2665-2675. CA 128:243858.

45 Liaoli Li, Qingqi Chen, Synthesis of Tetrahydrofuran Analogs, Huaxue Shiji, 1998, 20(5), 317. CA 130:38258(1999).

44. Bingzi Chen, Xiulin Ye, Qingqi Chen*, An Efficient and Highly Practical Synthesis of Tetrahydrofurofurane Lignans, Synthetic Communications 1998, 28(15), 2831-2841. CA 129:216455.

43. Qingqi Chen*, Xiaoli Li, and Bingzi Chen, An Efficient Route to 1,2-Bis(9’-bromodipyrrin)ethane, Synthetic Communications 1998, 28(18), 3359-3369. CA 129:275761.

1997

42. Xiaoli Li, Qingqi Chen*, An Improved Preparation of Tetrahydro-2,5-dimethoxyfuran, Chem. Res. Chin. Uni. 1997, 13(1), 89-90. CA 126:238263.

1996

41. Heinz Falk*, Qingqi Chen, Ronald Micura, On the Chemistry of Pyrrole Pigments, XCVII: Synthesis, Sterochemistry and Solvatoromic effect of 1-(dipyrr-1-one-9-ylene)-3-(dipyrrinone-9-yl)-propene-1: Monatshefte für Chemie (Chemical Monthly), 1996, 127(1), 77-83. CA: 124:342939c.

40. Heinz Falk*, Qingqi Chen, On the Chemistry of Pyrrole Pigments, XCVI: An Efficient Synthesis of Corrphycenes, Monatshefte für Chemie (Chemical Monthly), 1996, 127(1), 69-75. CA: 125:10444m

1995

39. Qingqi Chen, Heinz Falk, Ronald Micura, On the Chemistry of Pyrrole Pigments, XCII: Syntheses of 1,2-Bisdipyrrolylethanes, Monatshefte für Chemie (Chemical Monthly), 1995, 126, 473-479. CA 123:111721p.

38. Qingqi Chen, Jinshi Ma, Chongqi Wang, Yongyong Liu, Fan Yan, Lingjiang Cheng, Sheng Jin, and Heinz Falk, 1,2-Bis-dipyrrinone-ethene: a Novel b-Homo-verdin Chromophore: the Reaction of 9-Methyl-10H-dipyrrin-1-ones with Bromine, Monatshefte für Chemie (Chemical Monthly), 1995, 126, 983-991. CA 124:29494d.

37. Qingqi Chen, Heinz Falk, On the Chemistry of Pyrrole Pigments, XCIII: 1,2-bis(dipyrrinon-9-ylene)-ethane, A Novel b-Homo-biliverdins, Monatshefte für Chemie (Chemical Monthly), 1995, 126, 1097-1107. CA 124:29496f.

36. Qingqi Chen, Heinz Falk, On the Chemistry of Pyrrole Pigments, XCIV: 1-(Dipyrrinon-9-yl)-3-(dipyrrinone-9-ylene)-propene-1, A Novel b-Vinylogous Verdin Chromophore, Monatshefte für Chemie (Chemical Monthly), 1995, 126, 1233-1244. CA 124:86667m.

35. Qingqi Chen, Heinz Falk, On the Chemistry of Pyrrole Pigments, XCV: 1,4-Bis(dipyrrinone-9-ylene)-butene-2, A Novel b-Homoverdin Chromophore, Monatshefte für Chemie (Chemical Monthly), 1995, 126, 1323-1329.

34 Qingqi Chen, Fan Yan; Jinshi Ma, Sheng Jin, Syntheses of 1,2-Bis-[5-(2'-benzoxazolyl)-pyrrole-2-yl]-ethene, Dyes and Pigments 1995, 28(4), 291-295.

33. Qingqi Chen, Chongqi Wang, Lingjiang Cheng, Jinshi Ma, Sheng Jin, Synthesis and Intramolecular Hydrogen Bonding of Symmetric dipyrrylmethanes, Gaodeng Xuexiao Huaxue Xuebao = Chemical Journal of Chinese Universities, 1995, 16(5), 725-729. CA 123-256459u.

32. Jinshi Ma, Qingqi Chen, Chongqi Wang, Yongyong Liu, Fan Yan, Lingjiang Cheng, Sheng Jin, Heinz Falk, A Novel 16,24-Dehydrobiladiene-ab System: the Reaction of Xanthorubic Acid Methyl Ester with Bromine, Monatshefte für Chemie (Chemical Monthly), 1995, 126(2), 201. CA 122:290551g

31. Jinshi Ma, Qingqi Chen; Chongqi Wang, Lingjiang Cheng, Sheng Jin, Intramolecular Hydrogen Bonding in Symmetric Pyrro-methanes, Spectroscopy Letter 1995, 28(2), 223-230. CA 123:256459u

1994

30. Jinshi Ma; Qingqi Chen; Chongqi Wang; Sheng Jin; The Formation of 1,2-Bisdipyrrinone-Ethene, Chinese Chem. Lett. 1994, 5(12), 1017-20. CA 122-160338(1995).

29. Wang Qiu-An, Chen Qing-qi. Analytical Technology of Daily Chemical Flavor And Essence [J]. China Surfactant Detergent & Cosmetics, 1994, (2):36-41(Chinese).

28. Wang Qiu-An, Chen Qing-qi. Analytical Technology of Daily Chemical Flavor And Essence, Shanghai Light Industry 1994, 24(4), 22-26 (Chinese).

1993

27 Wang Qiu-An, Chen Qing-qi. Monitoring international new development, and suggestion to improve China’s Essence and Perfume Industry, Beijing Chemical Industry for Daily Necessitates, 1993, (2), 2-4 (Chinese).

26. Jinshi Ma, Chongqi Wang, Qingqi Chen, Yongyong Liu, Jingzhong Wang, Sheng Jin, Formation of 16,24-Dehydrobiladiene-ab From Pyrromethenone, Chinese Chem. Lett. 1993, 4(12), 1039-40. CA 121:35125 (1994)

25. Lingjiang Chen, Qingqi Chen, Hancheng Yuan, Jinshi Ma, Baozhen Yan, Guangzhi Xu, The Kinetic Studies on the Photoismerization of 1,2-Disubstituted Ethylenes, Chinese Chem. Lett. 1993, 4(4), 335. CA 120:76750m.

24. Qingqi Chen; Fan Yan, Jinshi Ma, Sheng Jin, A Facile Synthesis of 1,2-Bispyrroleethylenes, Chinese Chem Lett. 1993, 4(7), 567-568. CA 120-298398s.

1992

23. Qiu-An Wang, Qingqi Chen, Application of membrane separation technologies in food industry, Mechanics of Light Industry, 1992, (4), 4-8.

1991

22. Qingqi Chen, Absorbent Film Used as Preservative for Foodstuff, Food Science , 1991, 6, 54-57.

1990

21. Qingqi Chen, Natural Organic Products Used as Food Antioxidative, Food Science, 1990, 121(1), 16-18. CA 113-38970f.

20. Qingqi Chen, Guiji, Jiang, Yongjun Gao, Application Research on Super Absorbent, Scienes & Technology of Food Industry, 1990, 57(1), 45-50.

19. Qingqi Chen, Deodorization of Fresh Garlic, J. Chinese Condiment, 1990, 24, 21-22. CA 115-181600.

18. Qingqi Chen, Yajun Hu, Manufacturing of Packing-Films Using Starch-based Plastic, Cereal and Oil, 1990, 1, 32-34.

17. Qingqi Chen, Zhuwan Li; Aimin Wang, Synthesis and application of Stable Chlorine Dioxide, Food Research and Development, 1990, 2, 11-17.

16. Qingqi Chen, Research on Starch-base Super Absorbent---Answer to Reader, Scienes & Technology of Food Industry, 1990, 1, 45-50.

15. Qingqi Chen, Zhenjun Wang, Syntheses of Starch-base Super Absorbent, Cereal and Oil, 1990, 4, 16-19.

1989

14. Qingqi Chen, Zhuwen Li; Aimin Wang, Natural Additives From Edible Materials to Improve Tobacco Quality, Part I, Food and Feed Additive Information, 1989, 3, 3-6.

13. Qingqi Chen, Zhuwen Li; Aimin Wang, Natural Additives From Edible Materials to Improve Tobacco Quality, Part II, Food and Feed Additive Information, 1989, 4, 8-12.

12. Qingqi Chen; Zhuwen Li; Wang, Aimin Wang; Natural Additives From Edible Materials to Improve Tobacco Quality, Part III, Food and Feed Additive Information, , 1989, 5, 36-37.

1988

11. Qingqi Chen, Nature Products Used in Food Preservation, Science & Technology of Food Industry, 1988, 46(1), 34-36.

10. Qingqi Chen; Li, Xiaoli; Recent Development on Research of Food Deodorants, Food Research and Development,1988, 4, 13-14.

9. Qingqi Chen; Yuxiang Zhang, Storing and Preservative Methods of Strawberry, Scienes & Technology of Food Industry, 1988, 5, 32-35.

8. Qingqi Chen; Xiaoli Li, New Trend on Research and Development of Starch Products, Food Research and Development, 1988, 4, 13-14.

7. Qingqi Chen, Food Preservatives Containing Ferreous Compounds, Shanghai Food Technology, 1988, 3, 48-50.

6. Qingqi Chen, Natural Products Used for Antioxidation of Edible Oil, Food and Feed Additive Information, 1988, 1, 1-3.

1987

5 Qingqi Chen, Xiaoli Li, Bulletin of Changchun Normal College (Natural Science Version), 1987, 8(2), 44-52.

1986

4 Qingqi Chen, Bulletin of Chenzhou Normal College (Natural Science Version), 1986, 6(1), 55-66.

3 Qingqi Chen; Xiaoli Li; New Method to Predict Chemical Shifts of Substituted Aromatic Compounds, Bulletin of Changchun Normal College (Natural Science Version), 1986, 7(2), 54-67.

1984

2 Qingqi Chen; Bulletin of Chenzhou Normal College (Natural Science Version), 1984, 4(3), 25-36.

1 Qingqi Chen, Study on Mechanism of Ozonlysis of Olefins, Bulletin of Chenzhou Normal College (Natural Science Version), 1984, 4(2), 59-64

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